A procedure for the preparation of human serum as control or standard for common clinical determinations was developed.Alternative sources of standard/control serum from bovine and porcine serum, expired plasma, and placental serum were explored. Bovine serum was found to be the best alternative.Fasting blood sugar level (FBS), BUN, creatinine, cholesterol and uric acid levels in pooled sera were monitored for stability.Stability of these analytes in pooled sera was found to be affected by the following: (a) state; (b) use of preservative; (c) length of storage time; and (d) storage temperature.
To develop the technology for the preparation of human/animal sera as controls/standards for common clinical chemistry determinations i.e. glucose, urea nitrogen, creatinine, uric acid and cholesterol.
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