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HERDIN Record #: PCHRD13091810515842 Submitted: 18 September 2013 Modified: 09 March 2020

Prevalence of dengue infection and accuracy of the rapid dengue-NS1 antigen strip test as a screening tool for dengue infection among patients presenting with fever at the emergency room of St. Luke's Medical Center (A prospective study).

AnnaKristine A. Ramos,
Faith Joan C. Mesa-Gaerlan,
Peter F. Quilala,
Cynthia A. Mapua,
Lady-Anne C. Suarez,
Hannah Karen M. Labayo,
Maria Luisa G. Daroy,
Ronald R. Matias,
Filipinas F. Natividad

Dengue infection, an arthropod-borne disease spread by the Aedes aegypti mosquito, is a major cause of morbidity and mortality in the Philippines, where epidemics occur every 3 to 4 years and cases increase to as high as 88% every year. This study has determined the accuracy of the dengue-NS1 test as a screening tool for dengue infection among patients with fever for 1 to 3 days presenting at the emergency room of the St. Luke's Medical Center. After enrolling 147 participants, the study found out that the dengue-NS1 strip test had a sensitivity of only 20% when compared to IgM-capture ELISA and 23.4% when compared to PCR/ viral culture. Specificity, however, was high at 80% when compared to IgM-capture ELISA and 86.7% when compared to PCR/ viral culture. The dengue-NS1 strip test excludes the diagnosis of dengue infection 65 to 68% of the time and confirms it in only 43%.

Publication Type
Publication Sub Type
Journal Article, Original
St. Luke's Journal of Medicine
Publication Date
January-June 2012
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Fulltext %2 (Request Document)
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