Background. Pulmonary artery sarcoma is a rare tumor that is often confused with chronic thromboembolic disease and have poor prognosis.
Case Presentation. We report two (2) cases of pulmonary artery sarcoma presenting with signs and symptoms of venous thromboembolism, which after thorough diagnostic work-up showed the presence of mass lesion at the pulmonary artery. We aim to strategize a multi modality management utilizing surgery, immunocell therapy and MTT (Molecular Targeted Therapy) to improve survival.
Conclusion. Pulmonary artery sarcoma is often mistaken for acute pulmonary embolism. Early diagnosis and proper imaging technique may prompt aggressive intervention. Multimodality treatment with immunocell therapy as an adjunct may improve survival.