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HERDIN Record #: NCR-PHC-18062714055068 Submitted: 27 June 2018 Modified: 27 June 2018

Differences in atherosclerotic profiles between patients with thoracic and abdominal aortic aneurysms among Filipinos.

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Background: Atherosclerosis has been classically and traditionally linked with aortic aneurysm in terms of etiopathogenesis. Studies however show that atherosclerotic profile of thoracic and abdominal aortic aneurysms differ and this has an impact not only in management and approach of patients with aortic aneurysms but also in the primary preventive aspect which is risk factor modifications.

Method: Retrospective study of 108 patients from the Philippine Heart Center from 2005 to 2009. Clinical variables were compared between patients with TAA and those with AAA by using a univariate anaysis.

Results: Although not statistically significant. the incidence of CAD among patients with AAA was higher than that or patients with TAA [10 patients (83%) vs. 13 patients (72%), p =0.7977: OR .52, 95% CI (0.08 to 3.25), p=0.485]. Presence of historical risk factors or cerebrovascular disease (CVD), Myocardial Infarction (MI), Peripheral Arterial Disease (PAOD), Diabetes Mellitus (DM2), Hypertension and Chronic Obstructive Pulmonary Disease(COPD) did not show statistically significant differences between patients with AAA and TAA. Concomitant 3-vessel CAD was round to be statistically signficantly more common among patients with AAA than TAA [14%, vs. 5. 6%, p = 0.012].

Conclusion: Clinically significant CAD prevalence in patients with aortic aneurysm is high, especially those with abdominal aortic aneurysms.

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Philippine Heart Center Medical Library PHC.IR.012.09 Fulltext Print Format